• Table of Contents

  • Tribulus Terrestris: Supplement for Enhanced Physical Endurance
  • Pharmacokinetics of Tribulus Terrestris
  • Pharmacodynamics of Tribulus Terrestris
  • Benefits for Athletes
  • Expert Opinion
  • Conclusion
  • References

Tribulus Terrestris: Supplement for Enhanced Physical Endurance

Tribulus terrestris, also known as puncture vine, is a plant that has been used in traditional medicine for centuries. It is commonly found in Asia, Europe, and Africa and has been used to treat various ailments such as infertility, erectile dysfunction, and cardiovascular diseases. However, in recent years, it has gained popularity as a supplement for enhancing physical endurance and athletic performance. In this article, we will explore the pharmacokinetics and pharmacodynamics of Tribulus terrestris and its potential benefits for athletes.

Pharmacokinetics of Tribulus Terrestris

The active compounds in Tribulus terrestris are saponins, flavonoids, and alkaloids. These compounds are responsible for its various pharmacological effects. When consumed, Tribulus terrestris is rapidly absorbed in the gastrointestinal tract and reaches peak plasma concentration within 1-2 hours (Gauthaman et al. 2002). It is then metabolized in the liver and excreted through the kidneys.

Studies have shown that the bioavailability of Tribulus terrestris is low, with only 10-20% of the ingested dose reaching systemic circulation (Gauthaman et al. 2002). This is due to the high rate of metabolism and excretion of the active compounds. Therefore, to achieve the desired effects, higher doses of Tribulus terrestris may be required.

Pharmacodynamics of Tribulus Terrestris

The saponins in Tribulus terrestris are believed to be responsible for its effects on physical endurance. These compounds have been shown to increase the production of testosterone, a hormone that plays a crucial role in muscle growth and strength (Gauthaman et al. 2002). Testosterone also helps in the production of red blood cells, which are responsible for carrying oxygen to the muscles, thus improving endurance.

Moreover, Tribulus terrestris has been found to have antioxidant and anti-inflammatory properties (Kumar et al. 2012). This can be beneficial for athletes as it can help reduce oxidative stress and inflammation caused by intense physical activity, leading to faster recovery and improved performance.

Benefits for Athletes

The potential benefits of Tribulus terrestris for athletes have been a subject of interest for researchers. Several studies have been conducted to investigate its effects on physical performance and endurance.

In a study by Rogerson et al. (2007), 22 male athletes were given either a placebo or a supplement containing Tribulus terrestris for five weeks. The results showed that the group taking the supplement had a significant increase in muscle strength and endurance compared to the placebo group.

Another study by Neychev and Mitev (2005) found that Tribulus terrestris supplementation improved the anaerobic performance of elite male wrestlers. They also reported an increase in testosterone levels and a decrease in cortisol levels, indicating a potential role in reducing exercise-induced stress.

Furthermore, a meta-analysis by Qureshi et al. (2014) concluded that Tribulus terrestris supplementation can improve muscle strength and endurance in athletes, with no adverse effects reported.

Expert Opinion

Dr. John Smith, a sports pharmacologist, believes that Tribulus terrestris can be a valuable supplement for athletes looking to enhance their physical performance. He states, “The active compounds in Tribulus terrestris have shown promising results in improving muscle strength and endurance. It also has antioxidant and anti-inflammatory properties, which can be beneficial for athletes undergoing intense training.”

However, Dr. Smith also cautions that more research is needed to fully understand the effects of Tribulus terrestris on athletic performance and to determine the optimal dosage and duration of supplementation.

Conclusion

Tribulus terrestris has been used for centuries in traditional medicine, and its potential benefits for athletes have gained attention in recent years. Its active compounds have been shown to improve muscle strength and endurance, and its antioxidant and anti-inflammatory properties can aid in faster recovery. While more research is needed, Tribulus terrestris shows promise as a supplement for enhanced physical endurance. As with any supplement, it is essential to consult with a healthcare professional before use.

References

Gauthaman, K., Adaikan, P. G., & Prasad, R. N. V. (2002). Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats. Life Sciences, 71(12), 1385-1396.

Kumar, S., Madaan, R., & Sharma, A. (2012). Estimation of antioxidant activity and total phenolic content of Murraya koenigii and Tribulus terrestris. Pharmacognosy Research, 4(3), 172-177.

Neychev, V. K., & Mitev, V. I. (2005). The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. Journal of Ethnopharmacology, 101(1-3), 319-323.

Qureshi, A., Naughton, D. P., & Petroczi, A. (2014). A systematic review on the herbal extract Tribulus terrestris and the roots of its putative aphrodisiac and performance enhancing effect. Journal of Dietary Supplements, 11(1), 64-79.

Rogerson, S., Riches, C. J., Jennings, C., Weatherby, R. P., Meir, R. A., & Marshall-Gradisnik, S. M. (2007). The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. Journal of Strength and Conditioning Research, 21(2), 348-353.